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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1893281Generated: October 25, 2026

4-Bromobenzamide → 4-(8-Hydroxy-1,4-dioxa-spiro[4.5]dec-8-yl)-benzamide

https://huagongshe.com/reaction/1893281

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BromobenzamideHCID 69683—
Reactant1,4-Dioxaspiro[4.5]decan-8-oneHCID 567415—
Product4-(8-Hydroxy-1,4-dioxa-spiro[4.5]dec-8-yl)-benzamideHCID 59541979—

Reaction Steps

The title compound was prepared as a white solid from 4-bromobenzamide (Aldrich) and 1,4-dioxa-spiro[4.5]decan-8-one using the procedure described in Step A of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513229B2
Source datasetuspto-grants-2013_08
ORD IDord-ae53260f4b644e8e86dc7c2b577e503c
Source noteuspto-grants-2013_08