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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1893284Generated: October 27, 2026

4-Bromo-2-fluoroanisole → 8-(3-Fluoro-4-methoxyphenyl)-1,4-dioxaspiro[4.5]decan-8-ol

https://huagongshe.com/reaction/1893284

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2-fluoroanisoleHCID 75378—
Reactant1,4-Dioxaspiro[4.5]decan-8-oneHCID 567415—
Product8-(3-Fluoro-4-methoxyphenyl)-1,4-dioxaspiro[4.5]decan-8-olHCID 59541962—

Reaction Steps

The title compound was prepared as a white solid from 4-bromo-2-fluoro-anisole (Aldrich) and 1,4-dioxa-spiro[4.5]decan-8-one using the procedure described in Step A of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513229B2
Source datasetuspto-grants-2013_08
ORD IDord-7ebcbfad7cc344d9acf9d0a062889035
Source noteuspto-grants-2013_08