HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 2-Amino-N-[1-(4-phenyl-cyclohexyl)-azetidin-3-yl]-acetamide TFA salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | {[1-(4-Phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-carbamic acid tert-butyl ester | HCID 59541886 | — |
| Product | 2-Amino-N-[1-(4-phenyl-cyclohexyl)-azetidin-3-yl]-acetamide TFA salt | HCID 86646681 | — |
Reaction Steps
The title compound was prepared as colorless oil from the TFA de-protection of {[1-(4-phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-carbamic acid tert-butyl ester (as prepared in the previous step) using the procedure described in step E of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513229B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-412f630f983a4389bc1556ae71c4975c |
| Source note | uspto-grants-2013_08 |