HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Pyrrolidine → N-{[1-(4-Phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-2-pyrrolidin-1-yl-5-trifluoromethyl-benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Pyrrolidine | HCID 31268 | — |
| Edukt | 2-Fluoro-N-{[1-(4-phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-5-trifluoromethyl-benzamide | HCID 49763099 | — |
| Produkt | N-{[1-(4-Phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-2-pyrrolidin-1-yl-5-trifluoromethyl-benzamide | HCID 49763226 | — |
Reaktionsschritte
The title compound was prepared as a white solid from coupling of 2-fluoro-N-{[1-(4-phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-5-trifluoromethyl-benzamide (as prepared in Example 66) and pyrrolidine (Aldrich) using the procedure described in Example 69.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08513229B2 |
| Quelldatensatz | uspto-grants-2013_08 |
| ORD ID | ord-b47ea647184b4e04a12cc2d69f538262 |
| Quellennotiz | uspto-grants-2013_08 |