HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → N-(Azetidin-3-ylcarbamoylmethyl)-4-fluoro-3-trifluoromethyl-benzamide TFA Salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 3-[2-(4-Fluoro-3-trifluoromethyl-benzoylamino)-acetylamino]-azetidine-1-carboxylic acid tert-butylester | HCID 59541922 | — |
| Product | N-(Azetidin-3-ylcarbamoylmethyl)-4-fluoro-3-trifluoromethyl-benzamide TFA Salt | HCID 86646682 | — |
Reaction Steps
The title compound was prepared as colorless oil from the TFA de-protection of 3-[2-(4-fluoro-3-trifluoromethyl-benzoylamino)-acetylamino]-azetidine-1-carboxylic acid tert-butylester (as prepared in the previous step) using the procedure described in Step E of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513229B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-8c6cfddc8b3b42a08e72d240f58a4030 |
| Source note | uspto-grants-2013_08 |