HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylcyclohexanone → 4-Fluoro-N-{[1-(4-phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-3-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylcyclohexanone | HCID 78605 | — |
| Reactant | N-(azetidin-3-ylcarbamoylmethyl)-4-fluoro-3-trifluoromethyl-benzamide | HCID 59541942 | — |
| Product | 4-Fluoro-N-{[1-(4-phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-3-trifluoromethyl-benzamide | HCID 49763227 | — |
Reaction Steps
The title compound was prepared as a white solid by reductive amination of 4-phenyl-cyclohexanone (as prepared in the previous step) and N-(azetidin-3-ylcarbamoylmethyl)-4-fluoro-3-trifluoromethyl-benzamide using the procedure described in Step C of Example 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513229B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-a942ea2419e24e2f9abfce024983a14f |
| Source note | uspto-grants-2013_08 |