HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylcyclohexanone → 3-Fluoro-N-{[1-(4-phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-5-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylcyclohexanone | HCID 78605 | — |
| Reactant | HCID 59361623 | HCID 59361623 | — |
| Product | 3-Fluoro-N-{[1-(4-phenyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-5-trifluoromethyl-benzamide | HCID 49763343 | — |
Reaction Steps
The title compound was prepared as a white solid by reductive amination of 4-phenyl-cyclohexanone (Aldrich) and N-(azetidin-3-ylcarbamoylmethyl)-5-fluoro-3-trifluoromethyl-benzamide (as prepared in the previous step) using the procedure described in Step C of Example 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513229B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-0dc24102772740c99770ecc21a74293e |
| Source note | uspto-grants-2013_08 |