Phenylsulfamate → Sulfamic acid 1-trifluoroethyl-cyclopropyl ester

HRID 1893645노트

반응식

HRID 1893645 반응식
C1([O:7][S:8](=O)(=[O:10])[NH2:9])C=CC=CC=1.[F:12][C:13]([F:20])([F:19])[CH2:14][C:15]1([OH:18])[CH2:17][CH2:16]1>>[F:12][C:13]([F:20])([F:19])[CH2:14][C:15]1([O:18][S:8](=[O:10])(=[O:7])[NH2:9])[CH2:17][CH2:16]1

참가 물질

3

반응물 2

HCID 11030308PhenylsulfamateHCID 574451531-(2,2,2-Trifluoroethyl)cyclopropan-1-ol

생성물 1

HCID 57785491Sulfamic acid 1-trifluoroethyl-cyclopropyl ester

실험 절차

Sulfamic acid 1-trifluoroethyl-cyclopropyl ester was synthesized according to the method presented in the synthesis of sulfamic acid phenyl ester in Example 1 with the exception of utilizing 1-trifluoroethylcyclopropanol (synthesized by methods reported in Synthesis 1991, 234.) to obtain sulfamic acid 1-trifluoroethyl-cyclopropyl ester.

후처리

  1. customSulfamic acid 1-trifluoroethyl-cyclopropyl ester was synthesized

출처 및 근거

ORD 기록
ord-4ec91c2276e2487bb403e8facabb0875
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08513186B2

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