HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68618629, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | HCID 10682589 | HCID 10682589 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68618629 | HCID 68618629 | — |
Reaction Steps
A solution of 1-tert-butoxycarbonylamino-2-propyl-cyclopropanecarboxylic acid methyl ester (0.27 mmol) in THF (0.5 mL) was treated with 4M HCl in dioxane (2.4 mmol HCl). After 2 h, the volatiles are removed in vacuo to afford 1-amino-2-propyl-cyclopropanecarboxylic acid methyl ester hydrochloride salt as an amorphous white solid that was used without further purification (0.053 g, quant). LCMS found 157.9 ([M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513186B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-f2534ba88e7d46c2991733bbaae7d8fc |
| Source note | uspto-grants-2013_08 |