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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1893662Generated: November 1, 2026

Hydrochloric Acid → HCID 68618629, compound

https://huagongshe.com/reaction/1893662

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 10682589HCID 10682589—
SolventTetrahydrofuranHCID 8028—
ProductHCID 68618629HCID 68618629—

Reaction Steps

A solution of 1-tert-butoxycarbonylamino-2-propyl-cyclopropanecarboxylic acid methyl ester (0.27 mmol) in THF (0.5 mL) was treated with 4M HCl in dioxane (2.4 mmol HCl). After 2 h, the volatiles are removed in vacuo to afford 1-amino-2-propyl-cyclopropanecarboxylic acid methyl ester hydrochloride salt as an amorphous white solid that was used without further purification (0.053 g, quant). LCMS found 157.9 ([M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513186B2
Source datasetuspto-grants-2013_08
ORD IDord-f2534ba88e7d46c2991733bbaae7d8fc
Source noteuspto-grants-2013_08