HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3,4,5-tetrahydro-1H-1,5-benzodiazepine → HCID 57670143, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3,4,5-tetrahydro-1H-1,5-benzodiazepine | HCID 577192 | — |
| Reactant | (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride | HCID 57669958 | — |
| Product | HCID 57670143 | HCID 57670143 | — |
Reaction Steps
In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with 2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C38H42Cl2N5O2 [(M+H)+] 670.271, observed 670.2712.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513239B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-15481e17cf854793845cb8088a4150c2 |
| Source note | uspto-grants-2013_08 |