Hydrochloric Acid → HCID 136013808, compound

Participants

Reaction Steps

To N-{[5-(2-ethoxypyridin-3-yl)-1,3,4-thiadiazol-2-yl]methyl}-4-(2,4,6-trifluorobenzoyl)-1H-pyrrole-2-carboxamide (example 16) (102 mg, 021 mmol) was added 3 mL of 4M hydrogen chloride in 1,4-dioxane and the resulting suspension was stirred at rt for 7 hr. The reaction mixture was concentrated. The residue was triturated from dichloromethane to give the title compound (95 mg).

Provenance & Evidence