Hydrochloric Acid → 2-(1-Benzothiophen-7-Yl)-4-[1-(Piperidin-4-Yl)-1h-Pyrazol-4-Yl]furo[2,3-C]pyridin-7-Amine

HRID 189534Notes

Reaction equation

HRID 189534 reaction equation
[Cl:39][CH2:40][Cl:41].[ClH:38].[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:20]2[cH:21][n:22][n:23]([CH:25]3[CH2:26][CH2:27][N:28]([C:31]([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[CH2:29][CH2:30]3)[cH:24]2)[c:6]2[c:7]1[o:8][c:9](-[c:11]1[cH:12][cH:13][cH:14][c:15]3[cH:16][cH:17][s:18][c:19]13)[cH:10]2>>[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:20]2[cH:21][n:22][n:23]([CH:25]3[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]3)[cH:24]2)[c:6]2[c:7]1[o:8][c:9](-[c:11]1[cH:12][cH:13][cH:14][c:15]3[cH:16][cH:17][s:18][c:19]13)[cH:10]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 66760630tert-butyl 4-{4-[7-amino-2-(1-benzothiophen-7-yl)furo[2,3-c]pyridine-4-yl]-1H-pyrazol-1-yl}piperidine-1-carboxylate

Product 1

HCID 533792532-(1-Benzothiophen-7-Yl)-4-[1-(Piperidin-4-Yl)-1h-Pyrazol-4-Yl]furo[2,3-C]pyridin-7-Amine

Sources & evidence

ORD record
ord-981f4fbbf6514fd8b1c66362ddca8178
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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