HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → 2-(Pyridin-4-ylamino)-thiazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-(Pyridin-4-ylamino)-thiazole-4-carboxylic acid ethyl ester | HCID 2742075 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(Pyridin-4-ylamino)-thiazole-4-carboxylic acid | HCID 18186740 | — |
Reaction Steps
2-(Pyridin-4-ylamino)-thiazole-4-carboxylic acid (160 mg) was prepared according to General Procedure C using 2-(pyridin-4-ylamino)-thiazole-4-carboxylic acid ethyl ester in methanol:tetrahydrofuran:2N NaOH (1:1:1, 1.5 mL). The solvents were evaporated and the compound was dried. The crude product was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513430B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-8a86c1ceea4c4d9b870e0da0a508ccf4 |
| Source note | uspto-grants-2013_08 |