HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromopyruvic Acid → 2-[(2-Phenylethyl)amino]-4-thiazolecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromopyruvic Acid | HCID 70684 | — |
| Reactant | (2-Phenylethyl)thiourea | HCID 735845 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-[(2-Phenylethyl)amino]-4-thiazolecarboxylic acid | HCID 80567879 | 94.8% |
Reaction Steps
2-Phenethylamino-thiazole-4-carboxylic acid (235 mg) was prepared according to General Procedure B using phenethyl-thiourea (180 mg) and 3-bromo-2-oxo-propionic acid (167 mg) in methanol (2 mL). The crude product was used in a subsequent step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513430B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-9800e22d0b2b49ea99dc471d6019f74b |
| Source note | uspto-grants-2013_08 |