HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromopyruvic Acid → 2-(2-Pyridin-2-yl-ethylamino)-thiazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromopyruvic Acid | HCID 70684 | — |
| Reactant | [2-(Pyridin-2-yl)ethyl]thiourea | HCID 23143296 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(2-Pyridin-2-yl-ethylamino)-thiazole-4-carboxylic acid | HCID 80567914 | 90.9% |
Reaction Steps
2-(2-Pyridin-2-yl-ethylamino)-thiazole-4-carboxylic acid (375 mg) was prepared according to General Procedure B using (2-pyridin-2-yl-ethyl)-thiourea (300 mg) and 3-bromo-2-oxo-propionic acid (295 mg) in methanol (3 mL). The crude product was used in a subsequent step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513430B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-8abf9cd9a2474e27b46b08e393132b17 |
| Source note | uspto-grants-2013_08 |