HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromopyruvic Acid → 2-[(4-Methoxyphenyl)amino]-4-thiazolecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromopyruvic Acid | HCID 70684 | — |
| Reactant | 4-Thioureidoanisole | HCID 667549 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-[(4-Methoxyphenyl)amino]-4-thiazolecarboxylic acid | HCID 2759631 | 94.8% |
Reaction Steps
2-(4-Methoxy-phenylamino)-thiazole-4-carboxylic acid (237 mg) was prepared according to General Procedure B using (4-methoxy-phenyl)-thiourea (182 mg) and 3-bromo-2-oxo-propionic acid (200 mg) in methanol (2 mL). The crude product was used in a subsequent step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513430B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-f9afc583ba2b4e658d6c2505336d4a96 |
| Source note | uspto-grants-2013_08 |