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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1895873Generated: October 31, 2026

Formamide → 3,4-Dihydro-6-hydroxy-4-oxoquinazoline

https://huagongshe.com/reaction/1895873

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormamideHCID 713—
Reactant5-Hydroxyanthranilic acidHCID 164592—
Product3,4-Dihydro-6-hydroxy-4-oxoquinazolineHCID 135489577—

Reaction Conditions

Temperature190 °C

Reaction Steps

To a solution of 2-amino-5-hydroxybenzoic acid 0201 (30.6 g, 0.2 mol) in formamide was stirred and heated to 190° C. for 0.5 h. The mixture was allowed to cool to room temperature.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08518910B2
Source datasetuspto-grants-2013_08
ORD IDord-9fcb802f9d6f4c4eb02be2bdf3a4464c
Source noteuspto-grants-2013_08