反应详情

The title product was prepared following the procedure reported for the Compound of Example 45 but using phenylacetylene instead of instead of Compound 2b and Compound 66a instead of 5-bromonicotinonitrile. The residue coming from the usual work-up procedure was purified by flash chromatography (EtOAc—Petroleum Ether gradient from 5:95 to 10:90).

1. customwas purified by flash chromatography (EtOAc—Petroleum Ether gradient from 5:95 to 10:90)