HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-[3-(3,5-difluorophenyl)prop-2-yn-1-yl]piperidine-1-carboxylate → 4-[3-(3,5-Difluorophenyl)prop-2-ynyl]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-[3-(3,5-difluorophenyl)prop-2-yn-1-yl]piperidine-1-carboxylate | HCID 68726123 | — |
| Reactant | 2-Methyl-6-(3-piperidin-4-ylideneprop-1-ynyl)pyridine | HCID 87550402 | — |
| Product | 4-[3-(3,5-Difluorophenyl)prop-2-ynyl]piperidine | HCID 68979491 | — |
Reaction Steps
The title compound was prepared following the procedure described for the Compound of Example 3, using the Compound of Example 247 instead of the Compound of Example 2. After the usual work-up procedure, the crude was used for the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08518916B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-76778855337f410894fdcfa7854d8862 |
| Source note | uspto-grants-2013_08 |