HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 25181653, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Chloro-3-nitropyridine | HCID 79613 | — |
| Reactant | HCID 86627345 | HCID 86627345 | — |
| Product | HCID 25181653 | HCID 25181653 | 95.7% |
Reaction Steps
A well homogenised mixture of Compound 255b (175 mg, 0.878 mmol), 2-chloro-3-nitropyridine (153 mg, 0.966 mmol) and triethylamine (0.139 mL, 0.97 mmol) was stirred at 25° C. for 24 h. The reaction crude was purified by flash chromatography (EtOAc—Petroleum Ether 8:2) affording the title product (270 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08518916B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-b42f9352a8d848aea479a21e0c83407c |
| Source note | uspto-grants-2013_08 |