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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1896023Generated: November 1, 2026

2-chloro-5-phenylnicotinonitrile → HCID 87550659, compound

https://huagongshe.com/reaction/1896023

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-chloro-5-phenylnicotinonitrileHCID 2764043—
ReactantHCID 25181651HCID 25181651—
ProductHCID 87550659HCID 87550659—

Reaction Steps

Following the procedure reported above for the compound of Example 262 but replacing 5-(trifluoromethyl)pyridine with 2-chloro-5-phenylnicotinonitrile the title product was synthesized. After the reaction work-up, the residue was purified by automated flash liquid chromatography (Horizon™-Biotage) eluting with PE-EtOAc gradient from 9:1 to 4:6, affording the title product (10%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08518916B2
Source datasetuspto-grants-2013_08
ORD IDord-bbaa7addc1d44b32811dfa6a2c661ac3
Source noteuspto-grants-2013_08