Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Adenine → 9-(3-chloropropyl)-9H-purin-6-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Adenine | HCID 190 | — |
| 반응물 | 1-Bromo-3-chloropropane | HCID 8006 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 9-(3-chloropropyl)-9H-purin-6-amine | HCID 286591 | — |
반응 단계
A mixture of adenine, 1-bromo-3-chloropropane, and potassium carbonate in DMF was stirred at room temperature under argon for 4 days, filtered and evaporated to dryness. The crude product was washed with water and dried. Recrystallization from ethanol gave 9-(3-chloropropyl)adenine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08518885B2 |
| 출처 데이터셋 | uspto-grants-2013_08 |
| ORD ID | ord-ca790394ac114b64a4566e76a750bf06 |
| 출처 메모 | uspto-grants-2013_08 |