反应详情

A mixture of 1-(3-chloropropyl)-N4-acetylcytosine and sodium azide in acetonitrile was refluxed for 24 hours, cooled to room temperature, and filtered. The crude product was purified by silica gel column chromatography and gave 1-(3-azidopropyl)-N4-acetylcytosine as a white solid.

1. temperaturewas refluxed for 24 hours
2. filtrationfiltered
3. customThe crude product was purified by silica gel column chromatography