HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Azide → 1-(3-azidopropyl)-N4-acetylcytosine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 1-(3-chloropropyl)-N4-acetylcytosine | HCID 58166061 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-(3-azidopropyl)-N4-acetylcytosine | HCID 12212766 | — |
Reaction Steps
A mixture of 1-(3-chloropropyl)-N4-acetylcytosine and sodium azide in acetonitrile was refluxed for 24 hours, cooled to room temperature, and filtered. The crude product was purified by silica gel column chromatography and gave 1-(3-azidopropyl)-N4-acetylcytosine as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08518885B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-22bed8918a904e0f99a56764c3d8cf7c |
| Source note | uspto-grants-2013_08 |