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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1896252Generated: November 1, 2026

Ammonia → HCID 22716506, compound

https://huagongshe.com/reaction/1896252

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 12819459HCID 12819459—
ProductHCID 22716506HCID 2271650671.3%

Reaction Conditions

Temperature70 °C

Reaction Steps

Methanolic ammonia (10 ml) was added to methyl 2-(thiophen-2-yl)propanoate (200 mg, 1.17 mmol) in sealed tube, the reaction mixture was heated to 70° C. for 18 h. The volatiles were evaporated and the residue was washed with n-pentane to afford 130 mg (71.3%) of 2-(thiophen-2-yl)propanamide as brown color solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08518948B2
Source datasetuspto-grants-2013_08
ORD IDord-5943e8804078495ba67f0d9e9e5e800e
Source noteuspto-grants-2013_08