HRID1896313

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：COc1cc(F)ccc1-c1ccnc(NC(=O)[C@@H]2CC[C@H](NC(=O)OC(C)(C)C)C2)c1

HCID86657559

未命名化合物

PRODUCTS

生成物

结构：COc1cc(F)ccc1-c1ccnc(NC(=O)[C@@H]2CC[C@H](N)C2)c1

HCID67383230

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

(1R,3S)-3-Amino-N-(4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)cyclopentanecarboxamide was prepared according to Method C using tert-Butyl (1S,3R)-3-(4-(4-fluoro-2-methoxyphenyl)pyridin-2-ylcarbamoyl)cyclopentylcarbamate (1.00 g, 2.33 mmol), TFA (2 ml) in DCM (6 ml) starting at 0° C. which was allowed to warm up to room temperature and stirred for 2 h.

WORKUP

后处理

customstarting at 0° C.