HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 7-Bromo-1-[(4-methoxybenzyl)amino][1]benzothieno[3,2-c]pyridine-4-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 59198477 | HCID 59198477 | — |
| Product | 7-Bromo-1-[(4-methoxybenzyl)amino][1]benzothieno[3,2-c]pyridine-4-carbonitrile | HCID 59198465 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
A mixture of 7-bromo-1-chloro[1]benzothieno[3,2-c]pyridine-4-carbonitrile, 4-methoxybenzyamine (1 equiv) and K2CO3 (1 equiv) in DMF (0.3 M) was heated to 100° C. for 1 h. The mixture was poured into H2O, stirred for 15 min and filtered. The crude product was air dried over night and then heated to reflux in EtOH for 1 h, filtered and washed with EtOH to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08518964B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-cebb7c38b14148e4a66418b4a563df37 |
| Source note | uspto-grants-2013_08 |