HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1-Amino-7-bromo[1]benzothieno[3,2-c]pyridine-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Phosphate, Tribasic | HCID 62657 | — |
| Reactant | 7-Bromo-1-[(4-methoxybenzyl)amino][1]benzothieno[3,2-c]pyridine-4-carbonitrile | HCID 59198465 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 1-Amino-7-bromo[1]benzothieno[3,2-c]pyridine-4-carboxamide | HCID 23581929 | — |
Reaction Steps
A solution of 7-bromo-1-[(4-methoxybenzyl)amino][1]benzothieno[3,2-c]pyridine-4-carbonitrile in conc. H2SO4 (0.04 M) was stirred at room temperature for 2 h. The mixture was poured into H2O, neutralized with K3PO4, filtered, washed with H2O and dried. The crude product was swished with MeOH to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08518964B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-02a9646cb8124e57b6fa12c8db2d2fa2 |
| Source note | uspto-grants-2013_08 |