HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 59198485, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Potassium Phosphate, Dibasic | HCID 24450 | — |
| Reactant | 4-Methoxybenzylamine | HCID 75452 | — |
| Reactant | HCID 59198433 | HCID 59198433 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 59198485 | HCID 59198485 | — |
Reaction Steps
A mixture containing 1-chloro-7-(trifluoromethyl) [1]benzothieno[3,2-c]pyridine-4-carbonitrile, 4-methoxybenzylamine (2.2 equiv), K2CO3 (2.5 equiv) in DMF (0.15 M) was placed in a microwave reactor at 120° C. for 10 min. The reaction was diluted with H2O, the pH adjusted to 4 with HCl and K2HPO4 solution, and the title product was isolated by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08518964B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-2b51b68c3cb24559947cd0388069bfeb |
| Source note | uspto-grants-2013_08 |