N-methyl-2-pyrrolidone → HCID 178510359, compound

HRID 1896553Notes

Reaction equation

HRID 1896553 reaction equation
Br[C:2]1[C:7]2[NH:8][C:9]3[CH:10]=[C:11]([Cl:15])[CH:12]=[CH:13][C:14]=3[C:6]=2[C:5]([OH:16])=[N:4][CH:3]=1.[CH3:17][N:18]1C(=O)CCC1>>[OH:16][C:5]1[C:6]2[C:14]3[CH:13]=[CH:12][C:11]([Cl:15])=[CH:10][C:9]=3[NH:8][C:7]=2[C:2]([C:17]#[N:18])=[CH:3][N:4]=1

Participants

3

Reactant 2

HCID 13387N-methyl-2-pyrrolidoneHCID 178517585HCID 178517585, compound

Product 1

HCID 178510359HCID 178510359, compound

Procedure

The title compound was prepared from 4-bromo-7-chloro-5H-pyrido[4,3-b]indol-1-ol using the same procedure as described in example 5 step 3 except that the reaction was refluxing in NMP for 2 h.

Sources & evidence

ORD record
ord-a73d3ad6318341798f131bc58be09571
Source dataset
uspto-grants-2013_08
Patent number
US08518964B2

Reaction notes

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