反应详情

To CDI (1.6 g, 10 mmol) in acetonitrile (30 mL) was slowly added 2-aminobenzothiazole (1.0 g, 6.6 mmol) and allowed to stir at rt for 48 hours. The reaction mixture was filtered, washed with acetonitrile, and dried to provide 1.44 g (88%) of the desired product N-(benzo[d]thiazol-2-yl)-1H-imidazole-1-carboxamide (1M): LC/MS (APCI): m/z 245.1 (M+H).

1. filtrationThe reaction mixture was filtered
2. washwashed with acetonitrile
3. customdried