HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Piperidone → 1-(3-(6-(2-Fluorophenyl)pyridin-3-yl)propyl)piperidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Piperidone | HCID 12665 | — |
| Reactant | 5-(3-Bromopropyl)-2-(2-fluorophenyl)pyridine | HCID 69105979 | — |
| Product | 1-(3-(6-(2-Fluorophenyl)pyridin-3-yl)propyl)piperidin-2-one | HCID 16036652 | — |
Reaction Steps
50 mg (0.17 mmol) of 5-(3-bromopropyl)-2-(2-fluorophenyl)pyridine were reacted with 18.5 mg (0.18 mmol) of piperidin-2-one analogously to example 1d). Yield: 16 mg (31%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08518976B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-df95b7949afa463d87910924e2cebe44 |
| Source note | uspto-grants-2013_08 |