HCID 58562553, compound → HCID 58562755, compound

Participants

Reaction Steps

To a mixture of 8-(3,6-dihydro-2H-pyran-2-yl)-1,4-dioxaspiro[4.5]decane (190 mg, 0.847 mmol), as prepared in Example 2 step C, and Palladium on Carbon (118 mg, 0.055 mmol, 5%, “Degussa, wet”) was carefully added methanol (24 mL). The reaction flask was evacuated, backfilled with hydrogen via balloon and stirred at room temperature overnight. The catalyst was removed by filtration and the filtrate concentrated in vacuo to afford the product.

Provenance & Evidence