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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1896838Generated: November 1, 2026

Tetrabutylammonium Fluoride → 8-Hydroxy-8-(5-thiazolyl)-1,4-dioxaspiro[4.5]decane

https://huagongshe.com/reaction/1896838

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrabutylammonium FluorideHCID 2724141—
ReactantHCID 57803270HCID 57803270—
Product8-Hydroxy-8-(5-thiazolyl)-1,4-dioxaspiro[4.5]decaneHCID 59017441—

Reaction Steps

The title compound was prepared as white solid from 8-(2-trimethylsilanyl-thiazol-5-yl)-1,4-dioxa-spiro[4.5]decan-8-ol followed by TBAF work-up.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08518969B2
Source datasetuspto-grants-2013_08
ORD IDord-ff8a9ec72e5545f38fdb241c3d0ffbb4
Source noteuspto-grants-2013_08