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HRID1896917

反应详情

EQUATION

反应方程式

HRID 1896917 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+]
HCID5049666

Sodium triacetoxyborohydride

C6H10BNaO6

结构：CCOC(=O)CC1CCC(=O)CC1
HCID12666966

Ethyl (4-oxocyclohexyl)acetate

C10H16O3

结构：O=C(CNc1ncnc2ccc(C(F)(F)F)cc12)NC1CNC1
HCID68003594

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)CC1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1
HCID68004047

未命名化合物

PROCEDURE

实验过程

Reaction of ethyl 2-(4-oxocyclohexyl)acetate with N-(azetidin-3-yl)-2-((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamide (as prepared in Example 1 Step G) in the presence of TEA and NaBH(OAc)3 as described in Example 1, Step H afforded the product.

WORKUP

后处理

  1. customafforded the product