4-Methoxybenzyl alcohol → 4-Methoxybenzaldehyde

Participants

Reaction Steps

The effect of the additive was then examined for the oxidation of 4-methoxybenzylalcohol using 8 (2 mol %) in 1,2-dichloroethane (Table 2). Triethylamine, diisopropylethylamine, and TEMPO were all effective promoters of the vanadium complex, affording high yields of 4-methoxybenzaldehyde after 24 h at 60° C. (Entries 2 to 5). In contrast, less than 5% yield was observed with the vanadium complex alone (no additive, Entry 1), suggesting a key role for the nitrogen base.

Provenance & Evidence