反应详情

6-fluoro-2-naphthoic acid (2 g, 10.52 mmol) was stirred in thionyl chloride (21.03 ml) at 80° C. for 4 h in pressure vessel. The mixture was cooled and concentrated. The acid chloride was dried and used as is for next step.

1. temperatureThe mixture was cooled
2. concentrationconcentrated
3. dry with materialThe acid chloride was dried