Benzaldehyde → N-Benzylidene(piperidin-4-yl)methanamine

HRID 1897622Notes

Reaction equation

HRID 1897622 reaction equation

[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:9][CH2:10][CH:11]1[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]1>C1(C)C=CC=CC=1>[NH:14]1[CH2:15][CH2:16][CH:11]([CH2:10][N:9]=[CH:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[CH2:12][CH2:13]1

Participants

4

Reactant 2

HCID 240Benzaldehyde

HCID 235274-(Aminomethyl)piperidine

Product 1

HCID 11820173N-Benzylidene(piperidin-4-yl)methanamine

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Benzaldehyde (12.7 g; 0.12 mol) was added dropwise to a solution of 4-aminomethylpiperidine (13.7 g; 0.12 mol) in toluene (50 ml).

Sources & evidence

ORD record: ord-1dbb54ad54a04de3afaba0c36fd5743d
Source dataset: uspto-grants-2013_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08519139B2

Reaction notes

Loading…