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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1897960Generated: October 31, 2026

Hydrochloric Acid → HCID 66890171, compound

https://huagongshe.com/reaction/1897960

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactanttert-butyl 4-((6-((1-tert-butyl-1H-pyrazol-5-yl)amino)pyridin-2-yl)methyl)-4-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)piperidine-1-carboxylateHCID 66889439—
SolventMethanolHCID 887—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66890171HCID 66890171—

Reaction Steps

To a solution of 250 mg of tert-butyl 4-((6-((1-tert-butyl-1H-pyrazol-5-yl)amino)pyridin-2-yl)methyl)-4-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)piperidine-1-carboxylate in 4 ml of methanol was added 4 ml of 4 M hydrogen chloride in 1,4-dioxane at room temperature. The reaction mixture was stirred at room temperature for 1 hour, and concentrated in vacuo to give the title compound as a pale yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08519136B2
Source datasetuspto-grants-2013_08
ORD IDord-b2184f9ff760414fa48b591b68b3be70
Source noteuspto-grants-2013_08