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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1898200Generated: November 1, 2026

HCID 57942393, compound → HCID 44178044, compound

https://huagongshe.com/reaction/1898200

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57942393HCID 57942393—
SolventDichloromethaneHCID 6344—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 44178044HCID 44178044—

Reaction Steps

3-{[5-Chloro-3-(4-chloro-3-trifluoromethyl-benzenesulfonylamino)-pyridine-2-carbonyl]-ethyl-amino}-indazole-1-carboxylic acid tert-butyl ester was dissolved in a mixture of DCM and TFA (1:1) (5 mL). It was stirred at RT for 1 hour, concentrated, purified with HPLC to give 5-chloro-3-(4-chloro-3-trifluoromethyl-benzenesulfonylamino)-pyridine-2-carboxylic acid ethyl-(1H-indazol-3-yl)-amide. MS m/z: 557.9 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08519135B2
Source datasetuspto-grants-2013_08
ORD IDord-24fdc2750fbb4d9fb58bbe76cc14ff56
Source noteuspto-grants-2013_08