3-Amino-2-bromo-5-chloropyridine → HCID 58268262, compound

HRID 1898243Notes

Reaction equation

HRID 1898243 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](Cl)(=[O:10])=[O:9])=[CH:4][C:3]=1[CH2:12][CH3:13].[Br:14][C:15]1[C:20]([NH2:21])=[CH:19][C:18]([Cl:22])=[CH:17][N:16]=1>N1C=CC=CC=1>[Br:14][C:15]1[C:20]([NH:21][S:8]([C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[C:3]([CH2:12][CH3:13])[CH:4]=2)(=[O:10])=[O:9])=[CH:19][C:18]([Cl:22])=[CH:17][N:16]=1

Participants

4

Reactant 2

HCID 27696403-Amino-2-bromo-5-chloropyridineHCID 58268035HCID 58268035, compound

Product 1

HCID 58268262HCID 58268262, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Prepared from 1.71 g (7.15 mmol) of 4-chloro-3-ethyl-benzenesulfonyl chloride and 1.34 g (6.47 mmol) of 2-bromo-5-chloro-pyridin-3-ylamine in 4 mL pyridine using procedure x. Yield: 2.35 g of a white solid. LC-MSD, m/z for C13H11BrCl2N2O2S [M+H]+=408.8, 410.8, 412.8

Sources & evidence

ORD record
ord-dfb5bd4a7c6044c2acb17613ee222365
Source dataset
uspto-grants-2013_08
Patent number
US08519135B2

Reaction notes

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