3-Amino-2-bromo-5-chloropyridine → HCID 58268301, compound

HRID 1898244Notes

Reaction equation

HRID 1898244 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([S:12](Cl)(=[O:14])=[O:13])[CH:8]=[CH:9][C:10]=1[Cl:11])([CH3:4])([CH3:3])[CH3:2].[Br:16][C:17]1[C:22]([NH2:23])=[CH:21][C:20]([Cl:24])=[CH:19][N:18]=1>N1C=CC=CC=1>[Br:16][C:17]1[C:22]([NH:23][S:12]([C:7]2[CH:8]=[CH:9][C:10]([Cl:11])=[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[CH:6]=2)(=[O:14])=[O:13])=[CH:21][C:20]([Cl:24])=[CH:19][N:18]=1

Participants

4

Reactant 2

HCID 27696403-Amino-2-bromo-5-chloropyridineHCID 58268146HCID 58268146, compound

Product 1

HCID 58268301HCID 58268301, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Prepared from 420 mg (1.57 mmol) of 3-tert-butyl-4-chloro-benzenesulfonyl chloride and 326 mg (1.57 mmol) of 2-bromo-5-chloro-pyridin-3-ylamine in 3 mL pyridine using procedure x. Yield: 0.48 g of a white solid. LC-MSD, m/z for C15H15BrCl2N2O2S [M+H]+=436.9, 438.8, 440.8.

Sources & evidence

ORD record
ord-2a5b55a4326145f78e73f42360fd4a4a
Source dataset
uspto-grants-2013_08
Patent number
US08519135B2

Reaction notes

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