3-Amino-2-bromo-5-chloropyridine → HCID 58268062, compound

HRID 1898245Notes

Reaction equation

HRID 1898245 reaction equation
[C:1]([C:4]1[CH:5]=[C:6]([S:11](Cl)(=[O:13])=[O:12])[CH:7]=[CH:8][C:9]=1[Cl:10])(=[O:3])[CH3:2].[Br:15][C:16]1[C:21]([NH2:22])=[CH:20][C:19]([Cl:23])=[CH:18][N:17]=1>N1C=CC=CC=1>[C:1]([C:4]1[CH:5]=[C:6]([S:11]([NH:22][C:21]2[C:16]([Br:15])=[N:17][CH:18]=[C:19]([Cl:23])[CH:20]=2)(=[O:13])=[O:12])[CH:7]=[CH:8][C:9]=1[Cl:10])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 27696403-Amino-2-bromo-5-chloropyridineHCID 431189053-Acetyl-4-chlorobenzene-1-sulfonyl chloride

Product 1

HCID 58268062HCID 58268062, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Prepared from 1.6 g (6.32 mmol) of 3-acetyl-4-chloro-benzenesulfonyl chloride and 1.3 g (6.28 mmol) of 2-bromo-5-chloro-pyridin-3-ylamine in 8 mL pyridine using procedure x. Yield: 1.3 g of a white solid. LC-MSD, m/z for C13H9BrCl2N2O3S [M+H]+=422.8, 424.8, 426.8.

Sources & evidence

ORD record
ord-a6fa1b10617f43ae91cd3e6a96f238a7
Source dataset
uspto-grants-2013_08
Patent number
US08519135B2

Reaction notes

Loading…