Chloromethyl Methyl Ether → HCID 58268053, compound

Participants

Reaction Steps

Prepared from 460 mg (1.03 mmol) of N-(2-bromo-5-chloro-pyridin-3-yl)-4-chloro-3-(1,1-difluoro-ethyl)-benzenesulfonamide, 355 mg of potassium carbonate and 195 μL of methoxymethyl chloride in 2 mL THF using procedure x. Yield: 162 mg of a white solid. LC-MSD, m/z for C15H13BrCl2F2N2O3S [M+H]+=488.8, 490.8, 492.8; HPLC retention time: 2.9 min.

Provenance & Evidence