Hydrogen iodide → HCID 178506563, compound

HRID 1898268Notes

Reaction equation

HRID 1898268 reaction equation
Cl[C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[N:4]=[CH:5][NH:6]2.[IH:11]>>[I:11][C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[N:4]=[CH:5][NH:6]2

Participants

3

Reactant 2

HCID 24841Hydrogen iodideHCID 178478393HCID 178478393, compound

Product 1

HCID 178506563HCID 178506563, compound

Conditions

Temperature
0 °C

Procedure

A mixture of 6-chloro-9H-purine (684 mg, 4.46 mmol) and 6 mL of 57% hydriodic acid were stirred at 0° C. for 1.5 h. The reaction yielded 840 mg of the product as a white powder. The solid was filtered off, suspended in 5 mL of water and brought to pH=8 with aqueous ammonia solution. The suspension was cooled down to 0° C. and the solid was filtered off, washed with cold water and dried to give the product.

Sources & evidence

ORD record
ord-94db51d6c2b241f2a29a190b3381dbad
Source dataset
uspto-grants-2013_08
Patent number
US08519135B2

Reaction notes

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