Hydrogen iodide → HCID 178506554, compound

HRID 1898270Notes

Reaction equation

HRID 1898270 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[NH:8][CH:9]=[N:10][C:3]=12.[IH:11]>>[I:11][C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[NH:8][CH:9]=[N:10][C:3]=12

Participants

3

Reactant 2

HCID 24841Hydrogen iodideHCID 178478247HCID 178478247, compound

Product 1

HCID 178506554HCID 178506554, compound

Procedure

A mixture of 7-chloro-3H-imidazo[4,5-b]pyridine (1.47 g, 9.64 mmol) and 15 mL of 57% hydriodic acid were reacted at 80° C. for 4 h. After the solid was filtered off it was resubmitted to the reaction with 10 mL of fresh 57% hydriodic acid. The reaction yielded 1.3 g of the product as a black powder, 90% pure.

Workup

  1. customwere reacted at 80° C. for 4 h
  2. filtrationAfter the solid was filtered off it
  3. customwas resubmitted to the reaction with 10 mL of fresh 57% hydriodic acid

Sources & evidence

ORD record
ord-aa8a22b4106347ec917b9abc2089866a
Source dataset
uspto-grants-2013_08
Patent number
US08519135B2

Reaction notes

Loading…