Sodium Hydroxide → HCID 86664689, compound

Participants

Reaction Steps

The title compound was prepared following the procedure described for step-2 of intermediate-3 using methyl 2-[(3,5-dichloropyridin-4-yl)amino]-7,7-dimethyl-7,8-dihydrofuro[2,3-g][1,3]benzothiazole-5-carboxylate (0.080 g, 0.188 mmol), methanol (2.0 mL) and (50%) aqueous solution of sodium hydroxide (0.200 g, 5.00 mmol) to afford 0.050 g of the desired product. 1HNMR (DMSO-d6): δ 1.43 (s, 6H), 2.98 (s, 2H), 7.37 (s, 1H), 7.30 (s, 1H), 8.61 (m, 2H), 12-13 (s, 1H); MS [M+H]+: 424.18.

Provenance & Evidence