Citric Acid → HCID 178422761, compound

Participants

Reaction Steps

To a solution of 2-[(2-chloro-6-fluorophenyl)amino]-7,7-dimethyl-N-[4-(trifluoromethyl)phenyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazole-5-carboxamide (Example-107, 0.100 g) in acetone was added citric acid. The reaction mass was refluxed for 3 h. The reaction mass was filtered and the obtained residue was washed with DEE to afford 0.100 g of the desired product.

Provenance & Evidence