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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1898441Generated: October 30, 2026

Hydrochloric Acid → HCID 178422741, compound

https://huagongshe.com/reaction/1898441

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 178422740HCID 178422740—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178422741HCID 178422741112.5%

Reaction Steps

The title compound was prepared following the procedure described for Example-146 using N-(4-bromophenyl)-2-[(2,6-dichlorophenyl)amino]-7,7-dimethyl-7,8-dihydro-1H-furo[3,2-e]benzimidazole-5-carboxamide (Example-11, 0.100 g), THF and conc. HCl to afford 0.060 g of the desired product. 1HNMR (DMSO-d6): δ 1.56 (s, 6H), 2.20 (s, 2H), 7.51-7.57 (m, 3H), 7.64-7.74 (m, 5H), 9.81 (s, 1H), 12.0-13.0 (br, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08519149B2
Source datasetuspto-grants-2013_08
ORD IDord-100934a16af748e3bce8053d06a46f10
Source noteuspto-grants-2013_08