Methanesulfonic Acid → 2-((3,5-Dichloropyridin-4-yl)amino)-N-(4-fluoro-3-(trifluoromethyl)phenyl)-7,7-dimethyl-7,8-dihydro-1H-benzofuro[4,5-d]imidazole-5-carboxamide Methanesulfonate

Participants

Reaction Steps

The title compound was prepared following the procedure described for Example-169 by using 2-((3,5-dichloropyridin-4-yl)amino)-N-(4-fluoro-3-(trifluoromethyl)phenyl)-7,7-dimethyl-7,8-dihydro-1H-benzofuro[4,5-d]imidazole-5-carboxamide (Example-196, 0.100 g), acetone, methanesulphonic acid to afford 0.051 g of the desired product. 1HNMR (DMSO-d6): δ 1.58 (s, 6H), 2.31 (s, 6H), 3.10 (s, 2H), 7.35 (s, m1H), 7.52 (t, J=9.9 Hz, 1H), 7.86 (m, 1H), 8.29 (m, 1H), 8.56 (s, 2H), 9.88 (s, 1H), 11-12.00 (br s, 4H).

Provenance & Evidence